proteinkeys

Computational Biology Center

proteinkeys

version 1.5.0 - trunk

Projects known functional residues in homologs on your protein of interest: SNPs, disease-associated mutations,
binding and phosphorylation sites, etc. Predicts new functional residues. Based on entropy analysis of a multiple
sequence alignment.

Find your protein in or browse through

Pfam families

Applications	plan mutation experiments that probe protein function predict the functional consequences of amino acid changes (e.g., SNPs) identify binding sites analyze specificity of protein-drug or protein-substrate interactions describe sequence changes that adapt protein function in evolution redesign protein interactions
Team	prediction method : Boris Reva, Chris Sander website, programming : Jack Antipin, Alexey Stukalov

Or analyze your own alignment :

upload your alignment text file in PFAM or FASTA format (2mb maximum) :

X

paste your alignment text in PFAM or FASTA format (2mb maximum)

reference sequence name :
If not specified, the name of the first sequence will be used


The specificity analysis will be done with default parameters; this is recommended only for those users who are in rush for the immediate results	This will go through 3 steps of computational protocol